San Diego Cruise Guide

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Panama Canal Cruises from San Diego

Three cruise lines offer cruises through the Panama Canal from San Diego. They are one-way trips that end in Florida or Texas. All go fully through the canal, and they visit resort ports along the way. See the schedule of departures below.

This time-lapse video shows a full transit of a cruise ship through the Panama Canal in just 5 minutes. The actual trip was more than 10 hours.

The Panama Canal is 100 years old, and is one of the engineering marvels of the world. A voyage through the canal is a real "must do" adventure. See an interesting 100 years of the Panama Canal in 10 photos gallery by PBS.

Panama Canal cruise itinerary

January 19, 2024: 15-day Panama Canal cruise on Holland America Line . One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puerto Caldera (Costa Rica), the Panama Canal, Cartagena (Colombia) and Half Moon Cay (Bahamas).

April 6, 2024: 15-day Panama Canal cruise on Holland America Line . One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puerto Caldera (Costa Rica), the Panama Canal, Cartagena (Colombia) and Half Moon Cay (Bahamas).

October 4, 2024: 16-day Panama Canal cruise on Holland America Line . One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), Puerto Caldera (Costa Rica), the Panama Canal, and Aruba.

October 10, 2024: 16-day Panama Canal cruise on Holland America Line . One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), Puerto Caldera (Costa Rica), the Panama Canal, and Aruba.

January 3, 2025: 15-night Panama Canal cruise on Holland America Line . One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puerto Caldera (Costa Rica), the Panama Canal, Cartagena (Colombia) and Half Moon Cay (Bahamas).

July 3, 2025: 20-night Panama Canal cruise on Oceania . One-way from San Diego to New York (New York). Visit Ensenada (Mexico), Cabo San Lucas (Mexico), Zihuatanejo (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puntarenas (Costa Rica), the Panama Canal, Cartagena (Colombia), Grand Cayman (Cayman Islands), Miami (Florida) and Port Canaveral (Florida).

October 9, 2025: 17-night Panama Canal cruise on Holland America Line . One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), Acajutla (El Salvador), Puntarenas (Costa Rica), the Panama Canal and Aruba.

October 18, 2025: 14-night Panama Canal cruise on Norwegian Cruise Line . One-way from San Diego to Miami (Florida). Visit Cabo San Lucas (Mexico), Acapulco (Mexico), Puerto Quetzal (Guatemala), Panama City (Panama), Cartagena (Colombia) and Grand Cayman (Cayman Islands).

November 1, 2025: 17-night Panama Canal cruise on Holland America Line . One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), Puntarenas (Costa Rica), the Panama Canal, Oranjestad (Aruba) and Half Moon Cay (Bahamas).

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Panama Canal Cruises

Set sail with princess® – the best panama canal cruise line.

Best Cruise Line Itineraries

13-Time Winner Recommend Magazine

We’re the number one cruise line sailing to this bucket list destination, and as awe-inspiring as it is to travel through one of  Condé Nast Traveler’s  7 Cruise Wonders of the World, we’ll help you explore equally fascinating places along the way. So stretch out on a Caribbean beach, admire the pristine rainforests, stroll the cobbled streets of colonial towns and journey through the fabled Panama Canal with Princess.

Roundtrip Ft. Lauderdale

From the East Coast

  • Roundtrip from Ft. Lauderdale
  • Experience a partial transit of the Panama Canal
  • Visit the pristine beaches of the Caribbean and explore the lush rainforests of Costa Rica
  • Uncover two or three of the ABC Islands (Aruba, Bonaire and Curaçao) and enjoy their vibrant culture and marine life

Between Atlantic & Pacific Oceans

Ocean to Ocean

  • Sail from the East Coast to the West Coast or vice versa. Cruise from Ft. Lauderdale to Los Angeles or San Francisco, or cruise from either of those two West Coast cities to Florida.
  • Ideal itinerary for those who want to experience a full transit of the Panama Canal
  • Transit all three sets of locks

Why Princess is the #1 Panama Canal Cruise Line

Meaningful travel to a bucket-list destination

Destination immersion

We craft our Panama Canal itineraries to enrich our guests' experiences to provide the most exposure to this bucket-list destination. You'll be enchanted by Spanish and Dutch cities dating back centuries, as well as diverse tropical rainforests, white-sand beaches, dramatic volcanoes and UNESCO World Heritage Sites. And Princess provides live narration from the bridge while transiting the locks, just one reason we were voted "Best Cruise Line for Enrichment" by  Cruise International .

Photo: Las Bovedas in Cartagena, Colombia

The leader in the Panama Canal

From ships custom built to sail the massive locks to immersive onboard programs and onshore adventures that inspire, Princess is the number one way to explore this epic phenomenon. We've sailed the Panama Canal since 1967 and we have more itinerary choices and departures of any cruise line in the region.

Photo: View of locks from the ship

Abundant adventures ashore

Each voyage offers a myriad of experiences and cultures. There is something for every type of explorer in this culturally diverse region. Choose from immersive excursions such as exploring the engineering mastery of the Canal, trekking through surrounding rainforests, visiting local villages and relaxing on the pristine beaches of the Caribbean.

Photo: Old City in Cartagena, Colombia

Panama Canal Cruise Articles and Videos

Find fascinating articles with Panama Canal cruise tips for experiencing unforgettable attractions, regional cuisine, and more on both sides of this epic man-made wonder.

2024-2025 Panama Canal Cruises

Sail through a man-made marvel. Discover Panama Canal with Princess Cruises.

San Juan del Sur Excursions: A Volcanic Adventure in Nicaragua

Have a volcanic adventure during San Juan del Sur excursions from Princess Cruises. Nicaragua excursions show you dynamic landscapes and exotic wildlife.

Top Five Panama Canal Shore Excursions and Attractions

From walking the ruins of Old Panama to a tram ride through Soberania National Park, you'll come back enriched and enlightened from your Panama Canal cruise.

Try These 6 Panamanian Foods on Your Panama Canal Cruise

Taste your way through the diverse culinary culture of Panama on your Panama Canal cruise with Princess.

Costa Rica Excursions: Something for Everyone

Partake in a Costa Rica excursion for a Caribbean adventure with Princess Cruises. There's something for everyone on Costa Rica shore excursions.

Panama Cruises Trivia: 5 Facts You Should Know About The Panama Canal

Test your knowledge of facts about the Panama Canal with Princess Cruises.

Travel, Airfare, & Hotels: Let Princess Get You There

Princess EZair® Flights

Stress-free airfare

Remove the hassle from air travel and give yourself the gift of flexibility, time, and a thicker wallet with Princess EZair flights. We negotiate lower rates with the airlines, allow you to modify your flight up to 45 days prior with no penalty, and protect you if your flight is late or canceled.

EZair flight quotes are available on our cruise search result details pages.

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We get you where you need to go

Let Princess pick you up from the airport and take you directly to your ship or hotel when you arrive, even if you didn't book your airfare through us. A uniformed Princess representative meets you at the airport after you've retrieved your luggage and transports you directly to your ship or hotel without you having to worry about the logistics of navigating a new city.

Cruise Plus Hotel Packages

Stay longer and relax

Extend your cruise vacation, and simplify your travel plans with a hotel stay at the beginning or end of your cruise. With a Cruise Plus Hotel Package, a Princess representative meets you at the airport and pier, transporting you to and from your hotel. The package includes the cost of your hotel stay, transportation, luggage handling, and the representative’s services.

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  • Daily housekeeping
  • Complimentary 24-hour room service
  • Elemis Aromapure soap, lotion, shampoo
  • Luxurious bathrobes
  • Hair dryers, makeup mirrors
  • Generous storage
  • Fresh fruit upon request
  • Ice service
  • TV with On Demand movies, programming

Two lower beds convertible to one queen-size bed—our signature Mariner's Dream™ bed with plush Euro-Top mattresses, premium massage shower heads and a host of amenities are featured in these comfortable staterooms.

These expansive staterooms include include two lower beds convertible to one queen-size bed—our Signature Mariner's Dream™ bed with plush Euro-Top mattresses, premium massage shower heads, a host of amenities and an ocean view.

Vista Suite

  • Whirlpool bath

With a verandah, floor-to-ceiling windows and comfortable sitting area, these comfortable suites are filled with light. They include two lower beds convertible to one queen-size bed—our signature Mariner's Dream™ bed with plush Euro-Top mattresses, plus a whirlpool bath and shower, mini-bar and refrigerator.

Neptune Suite

  • Premium bathrobes, slippers
  • One-Touch concierge service
  • In-suite coffee, espresso
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  • Pre-dinner hors d'oeuvres served in suite
  • Welcome glass of sparkling wine
  • Priority boarding for tender ports, priority dining/seating requests, special disembarkation service
  • High tea in suite on request
  • Exclusive tote bag

With floor-to-ceiling windows overlooking a private verandah, these spacious suites are flooded with light. They feature a large sitting area and two lower beds convertible to one king-size bed—our signature Mariner's Dream™ bed with plush Euro-Top mattresses. The bathroom comes with a dual-sink vanity, full-size whirlpool bath and shower, plus additional shower stall. Amenities include use of the exclusive Neptune Lounge, a private concierge and an array of complimentary services.

Your Ship: Zaandam

Designed to carry fewer guests while offering greater space, Zaandam is elegant and comfortable. Her décor is inspired by music and features musical instruments including signed guitars from Queen, Iggy Pop, Eric Clapton and the Rolling Stones and a Baroque-style pipe organ. While on board, rejuvenate with a spa treatment in the serene Greenhouse Spa & Salon®, indulge in a tantalizing meal at a fine dining restaurant or play a friendly game of pickleball at sea.

  • 1,432 Guests
  • 781 ft. Length
  • 105.8 ft. Width

Pool on the Lido deck of Zaandam cruise ship

Dining & Onboard Activities

Each day on board offers delicious dining options, world-class entertainment and enriching activities

Pinnacle Grill

The ultimate steakhouse at sea, with an exceptional menu of Prime steaks, seafood and wine.

Pinnacle Grill is the ultimate steakhouse at sea, where an exceptional menu and impeccable service make for one of finest meals you’ll ever have. The refined menu features a selection of 28-day wet-aged USDA Prime steaks — meticulously chosen to guarantee the finest quality — as well as classic steakhouse dishes and innovative recipes from James Beard Award-winning chef and Culinary Council® member, David Burke. Every dish is exquisitely prepared, beautifully plated and complemented by a vast collection of award-winning wines. Here, your meal is an event unto itself, a celebration of fine dining and a triumph of flavor.

*Meals at Pinnacle Grill are half price for kids 12 years old or under, or free when they order from the kids’ menu.

Canaletto is a relaxed setting with authentic Italian cuisine that is best enjoyed when shared.

In Italy, there’s nothing more important than coming together to celebrate the joy of great food. This is the inspiration for our onboard Italian restaurant, Canaletto. Enjoy amazing Italian classics like braised chicken cacciatore al forno, branzino ai ferri or garlic shrimp ravioli. And for dessert: tiramisù, cannoli alla Siciliana, gelato, and more. Including pasta made fresh daily. Buon Appetito!

Meals at Canaletto are half price for kids 12 years old or under, or free when they order from the kids’ menu.

Lido Market

A casual, modern marketplace, Lido Market offers the widest range of food options on board for breakfast, lunch, dinner and a late-night snack.

Explore a world of intriguing culinary possibilities in the Lido Market. Steps from the Lido pool, this modern marketplace includes a curated selection of delicious options that you can grab on the go or have made to order: Breadboard, with freshly baked breads and pastries; Wild Harvest, offering a bountiful selection of hearty salads; Homestead, serving up comfort classics; Distant Lands, featuring global cuisine; Sweet Spot, for ice cream creations and desserts; Roasting Pan, hand-carved meats, fish and other hearty entrees; Perk, freshly brewed beverages and chilled juices; Quench, premium coffee, beer, wine, and soda available for purchase; Rise, savory quiches, croissants and sandwiches, and more.

This casual poolside grill serves up the best burgers at sea, Nathan’s Famous gourmet hot dogs, golden French fries and more.

Dive-In offers a variety of casual culinary classics, using the highest quality ingredients. Enjoy a burger, grilled to perfection and served on a toasted brioche with our own trade-marked secret sauce. Savor a succulent Nathan’s Famous gourmet hot dog with golden French fries. Or choose a grilled chicken breast sandwich or juicy portabella mushroom stack. Dive-In is the perfect spot to dine poolside on the best burgers at sea.

24-Hour Room Service

Enjoy breakfast in bed or an early dinner on your verandah — entrées and more are available whenever you wish.

Sleep in and have breakfast delivered. Enjoy an early dinner on your verandah before an evening excursion. Order a salad, sandwich or entrée any time. Room Service is only a phone call away. All selections are included in your cruise fare unless otherwise noted on the in-room menu.

Morimoto By Sea (Pop-Up)

Masaharu Morimoto, our Fresh Fish Ambassador brings his innovative style to Morimoto by Sea, a specialty restaurant on board Nieuw Amsterdam and a pop-up dining experience on the rest of the fleet.

Chef Masaharu Morimoto, our Global Fresh Fish Ambassador brings his innovative style to Morimoto by Sea, a pop-up dining experience that will take over Tamarind or Pinnacle Grill at least once per cruise. The pop-up’s menu features artfully presented dishes, exclusive alcoholic beverages, and tantalizing desserts. Nieuw Amsterdam offers our full Morimoto by Sea restaurant.

The Dining Room

Our flagship dining experience is a welcoming and sophisticated setting for an exquisite breakfast, lunch or superb multicourse dinner.

For an elegant breakfast, leisurely lunch or unforgettable multi-course dinner, The Dining Room is your destination. For dinner, choose from classics such as Boneless Lamb Loin en Croute, Rosemary Roasted Chicken, as well as regionally inspired cuisine and artfully prepared vegetarian dishes. 

Crow's Nest

BARS AND LOUNGES

Enjoy cocktails and sunsets in this lounge, featuring panoramic views.

Holland America Line offers you a wide selection of lounges onboard. The panoramic view takes center stage in The Crow's Nest at the top of the ship, where you can relax just about any time of day and enjoy your favorite drink.

Explorer's Lounge

Elegant and refined, stop by for a glass of wine or your favorite cocktail.

The Explorer’s Lounge is an elegant and refined space to enjoy a glass of wine, a cocktail, or your favorite liqueur.

Enjoy a mix of three specialty bars: Champagne, Martinis, Spirits and Ales.

Holland America Line offers you a wide selection of lounges and gathering places onboard. Explore Mix for Champagne, Martinis, and Spirits and Ales.

Enjoy cocktails and ocean views while listening to live music.

Holland America Line offers you a wide selection of lounges. This popular bar is at the top of the atrium and is the perfect locale for cocktails and dancing.

Sea View Bar

Enjoy your favorite poolside drink while soaking up the sun and taking in panoramic views from the comfort of our deck lounge chairs. 

World Stage

ENTERTAINMENT

World Stage features innovative cruise ship shows and a two-story LED screen that creates a vivid wraparound display.

World Stage, the largest theater on board is home to a variety of performances day and night. Our exclusive EXC® Talk lecture series features captivating regional stories told by local experts and narrated by your Cruise & Travel Director. In the evenings, Step One Dance Company, vocal sensation Cantaré, BBC Earth in Concert and more take the stage.  Koningsdam, Nieuw Statendam  and  Rotterdam  bring the World Stage experience to the next level by surrounding you in spectacular sight and sound with a two-story, panoramic LED screen.

Onboard Shopping

Enjoy a wide variety of duty-free shopping onboard.

Enjoy a wide variety of duty-free shopping in such signature shops as The Vault, Diamonds and Gemstones by Merabella, which offers the best diamonds at sea, brought to you by Effy.

Fitness Center

Take a class in our professionally staffed Fitness Center.

Stop by the professionally staffed Fitness Center equipped with the latest cardio and weight machines. Try one of our classes on indoor cycling, Pilates and more or work out at your own pace. You can also head out for fresh air and exercise on deck, where you'll find basketball and volleyball courts, and two refreshing pools (available on select ships). Some classes may have a nominal fee.

Holland America Line Navigator

Personalize your cruise experience with our free mobile-friendly tool.

Personalize your cruise experience once you’re on the ship with our free mobile-friendly tool. Plan your daily activities, browse and purchase shore excursions, view restaurant menus, make dining reservations, check your account balance and more. 

Casino Action

The Casino offers games for all levels.

Your Holland America Line ship’s Casino offers a wide array of gaming options. Whether you prefer slot machines or want to try your hand at blackjack or poker, our dealers and staff are available to provide complimentary instruction — and we offer many engaging tournament options. The Casino is only open at sea.

Pickleball at Sea

Enjoy complimentary lessons, tournaments, and courts with amazing top-deck views.

Play the fastest-growing sport in the U.S. with Holland America Line, the exclusive cruise line partner of the Professional Pickleball Association. All our cruise ships feature pickleball courts with amazing top-deck views. The equipment and courts are available for a match anytime, so long as the weather allows. Frequent pickler? Join a pickleball tournament at sea and put your dink shot to the test. Hesitant amateur? Learn the basics at complimentary beginner’s lessons, starting in spring 2023. Commemorative starter kits will soon be available in our retail shops — purchase as gifts for avid players or as souvenirs, so that you can always look back on your pickleball cruise memories.

Kids ages 3 to 17 can enjoy an array of activities. Registration required for children under 13.

Holland America Line's youth activities program, Kids Club, offers an array of entertaining events for kids and teens ages 3-17, supervised by a full-time, professionally trained staff. They'll have an opportunity to join other kids their age for arts and crafts, sports, video game competitions, scavenger hunts, challenging team games and themed parties. Note: Kids Club is not offered on cruises of 25-days or longer, including all Legendary and Grand Voyages. We will offer a selection of children’s activities throughout these longer voyages for any children who may be onboard.

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15-Day Panama Canal

Amazing food and superb service make Holland America one of the longest running cruise lines.

Man-made and natural spectacles unite when you cruise to the unique Panama Canal.

Situated on the Pacific Ocean, San Diego is known for its near perfect weather, beautiful beaches and abundance of activities.

  • Zaandam - Passenger Capacity: 1,432 (double occupancy) Year Built: 2000 Last Refurbished: 2018

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San Diego, California , Cabo San Lucas, Mexico , Puerto Vallarta, Mexico , Huatulco, Mexico , Puerto Quetzal, Guatemala , Puntarenas, Costa Rica , Panama Canal, Panama , Cartagena, Colombia , Half Moon Cay (Little San Salvador Island), Bahamas , Fort Lauderdale (Port Everglades), Florida

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15-Day Panama Canal sailing on the Zaandam

Departure dates: jan 2025 - jan 2025.

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Take the world's greatest shortcut with our Panama Canal cruise.

Traversing the 40-mile Panama Canal is a rite of passage and something you'll remember for a lifetime. Add in compelling ports like Cartagena, Manzanillo and Puerto Vallarta on your Panama Canal cruise holiday , and you're in for a unique adventure. Depart from various cities, including Miami or Los Angeles, and cruise to some of the most exotic and beautiful destinations on Earth. Discover for yourself why Norwegian is the Best Cruise Line in Panama Canal & Central America according to Cruise Critic.

^Buy an air ticket and the 2nd guest flies for free. *View for full terms and conditions.

Award Winning Ships

Award Winning Ships

Travel across the Panama Canal in style on our award-winning ships. Voted Best Onboard Entertainment, Best Speciality Restaurants, and Best Casinos, you know you're in for an exciting cruise experience. Sit back, relax, and let Norwegian take you through one of the most magnificent marvels in the world.

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  • Belize City
  • Colonial Antigua
  • Oranjestad, Aruba
  • Cartagena, Colombia

Explore historical sites on your Panama Canal cruise

Explore Panama Canal Cruise Ports

cruise panama canal from san diego

Best Panama Canal EXCURSIONS

cruise panama canal from san diego

We know the destinations you'll be visiting and what there is to see, do and experience. We offer you a variety of excursions to choose from, in every port you'll visit.

cruise panama canal from san diego

Cave Of Wonders & Altos De Chavon

Explore a series of caverns decorated with pre-Columbian paintings and a hilltop village designed to replicate a 16th-century Mediterranean village. ...

cruise panama canal from san diego

Mexican Outback & Camel Ride

This Mexican Outback and Camel Safari is an unforgettable eco-adventure that combines spectacular views, delicious cuisine and an exciting beach camel ride....

cruise panama canal from san diego

Chileno Bay Snorkel

Cruise by the famed Lovers Beach, past the sea lion colony and the towering rock formations of Land’s End, then set sail for Chileno Bay. Here you'll discover the tropical fish and...

cruise panama canal from san diego

Safari Drive-Through

Visit one of the largest animal parks in Guatemala and from the comfort of your coach, you’ll see a variety of animals such as hippopotamus, giraffes, lions, zebras and more. ...

Panama Canal HOTELS

  • PANAMA CITY (PACIFIC CRUISE TERMINAL)
  • LOS ANGELES

cruise panama canal from san diego

Hilton Panama

Overlooking Panama Bay, this sophisticated hotel is 6 km from the Panamá Viejo historical district and 12 km from the Panama Canal locks.

The contemporary rooms offer free Wi-Fi, flat-screen TVs and iPod docks, plus minibars and desks. Some rooms feature balconies and/or bay views. Executive rooms and suites provide access to a lounge with complimentary continental breakfast, snacks and drinks.

The contemporary rooms offer free Wi-Fi, flat-screen TVs and iPod docks, plus minibars and desks. Some rooms feature balconies and/or bay views. Executive rooms and suites provide access to a lounge with complimentary continental breakfast, snacks and drinks. Suites add free-standing tubs and/or kitchens.

There are 2 elegant restaurants, including a steakhouse, as well as a trendy bar. Other amenities include a chic spa, a fitness centre and a rooftop pool with bay views.

Distance/Airport: 15 miles Distance/Pier: 20 miles

Package includes: Room and room tax Bellman gratuities Transfers between Airport and Hotel (via Hotel shuttle) Transfers between Hotel and Pier

Important Note: Accommodations are based on double occupancy per room. Some accommodation will allow triple and quad guests in a room and are subject to availability and surcharge will apply. Additional hotel rooms to accommodate triple and quads may be required, and surcharge will apply.

cruise panama canal from san diego

Hilton Checkers Los Angeles

Less than a mile from The Museum of Contemporary Art, this genteel hotel in a 1920s building is a mile both from the Walt Disney Concert Hall and from the Grammy Museum at L.A. Live.

Relaxed rooms offer flat-screen TVs, marble bathrooms and desks, as well as coffeemakers. Suites add separate living areas.

Relaxed rooms offer flat-screen TVs, marble bathrooms and desks, as well as coffeemakers. Suites add separate living areas. Some include patios and/or fireplaces.

There's a polished bar and an elegant restaurant. Other amenities include a fitness centre, a business centre and a rooftop terrace, plus meeting and event space.

Distance/Airport: 18 miles Distance/Pier: 23 miles

Package includes: Room and room tax Bellman gratuities Transfers between Hotel and Pier

cruise panama canal from san diego

The Sheraton Grand Los Angeles

Part of the Bloc shopping and entertainment centre, this upscale high-rise hotel is a minute's walk from a metro station, and less than a mile from the Crypto.com Arena.

Sophisticated rooms offer Wi-Fi, flat-screen TVs and coffeemakers; microwaves and minifridges are available on request. Suites add separate sitting areas. Club rooms provide access to a lounge with complimentary continental breakfast and afternoon snacks.

There's a hip restaurant featuring farm-to-table fare, and a lobby bar serving cocktails. Other amenities include a gym, plus 35,000 sq ft of meeting space.

Phone: (213) 488-3500

Distance/Airport: 17.5 miles Distance/Pier: 23 miles

Read THINGS TO KNOW ABOUT Panama Canal Cruises

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We Bet They'll Surprise You

Check out these 9 Things You Didn't Know About Cruising. Cruising with Norwegian means more dining and entertainment options than ever. Here's why.

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Over 60 million pounds of dynamite were used on the Panama Canal.

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There are at least 52 species of hummingbirds in Costa Rica.

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Colombia is responsible for 90% of the world's emeralds.

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Cruises from San Diego

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There’s a reason why San Diego is known as “America’s Finest City.” With year-round perfect weather, sunny beaches, and a charming atmosphere, San Diego is an inviting place that welcomes you with open arms. Visit its award-winning museums and zoos, ride a wave along its surf-friendly shores, and explore one of its many diverse neighborhoods full of restaurants, bars, and small boutiques.

Cruises from San Diego include itineraries along the Pacific Coast and through the Panama Canal to Fort Lauderdale. Discover the beauty of California during stops in Santa Barbara, Catalina Island, and San Francisco. Visit Astoria, Oregon and the bustling city of Seattle, Washington before disembarking in the modern metropolis of Vancouver. Or experience the thrill of cruising through the Panama Canal while discovering Central and South American destinations like Cartagena, Colombia and Puntarenas, Costa Rica along the way.

Please Note: While we don't currently sail to San Diego, you can still discover the beauty of the state on one of our California cruises . Browse our cruises to California below.

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Admire the engineering masterpiece of the Panama Canal, the water channel that connects the Atlantic and Pacific Oceans. During your journey, you’ll visit top beach destinations in Mexico, including Cabo San Lucas and Puerto Vallarta; the jungles of Costa Rica in Puntarenas; and the towns of Cartagena, Colombia and Puerto Quetzal, Guatemala, where colorful, colonial architecture is found at every turn.

From picturesque vineyards to gorgeous ocean views, all of the port destinations on a Pacific Coast cruise are a sight to behold. Overnight in the exciting city of San Francisco, where you can cross the Golden Gate Bridge or spend an afternoon touring Alcatraz. Sip on wine and stroll around the hills of California’s wine country. Embark on an outdoor adventure in Vancouver, head to the top of Seattle’s famous Space Needle, and stop by the Monterey Bay National Marine Sanctuary, one of the world’s best aquariums.

Our Ship Sailing out of San Diego

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Why Sail from San Diego with Celebrity Cruises

Cruise from San Diego in style on a Celebrity cruise. Stay in one of our spacious accommodations and enjoy unbeatable views of the Pacific Coast, or experience the magic of crossing the iconic Panama Canal from the comfort of your own veranda. 

By day, visit stunning port destinations in California and Canada, or Central and South America. Spend the evenings dining in one of our world-class restaurants, watching spectacular shows at the theater, and sipping on artisanal cocktails in one of our bars and lounges. There’s no shortage of fun and relaxation waiting for you on board.

View All Cruises from San Diego

San diego cruise port facilities & location.

Cruises from San Diego depart from the modern B Street Cruise Terminal and Broadway Pier. Here, you'll find souvenir shops and a beautiful park where you can sit and admire the beautiful view of the water. There is ample off-street parking available, with shuttles that will take you to the cruise terminal, as well as easy access via taxi or public transportation from the airport or downtown area.

Top Sights & Attractions for Cruises to & from San Diego

Mission beach.

Head to Mission Beach for a quintessential San Diego beach experience. Mission Beach is known for its miles of wide, golden sand and its bustling boardwalk full of rollerbladers and surfers enjoying the sunshine. It’s conveniently located adjacent to Belmont Park, a carnival-style amusement park with a wooden roller coaster and games.

Windansea Beach

For a more serene beach day, head north to Windansea Beach in La Jolla. Located in the laidback Bird Rock neighborhood, Windansea Beach is surrounded by large flat rocks that create the perfect hideaway to lay your towel over the powdery soft sand. While its secluded location may make you feel like you’re far away, you’ll be just a couple of blocks from coffee shops, cafes, and restaurants.

San Diego Zoo

The San Diego Zoo is considered one of the best zoos in the world, thanks to its incredible conservation efforts and large animal enclosures. Visitors of all ages will enjoy its wide variety of species and educational live shows. The San Diego Zoo is known for its panda exhibit, as it’s one of the few zoos outside of China where you can still see them in person. 

Learn More About San Diego Shore Excursions

Top things to do in san diego.

The USS Midway is an old naval aircraft carrier turned museum that is permanently docked in the harbor of San Diego. Learn about the area’s naval history and tour the control room, the sailors’ bunks, and the deck where fighter jets used to land on the ship. Don’t miss visiting the large statue of a sailor kissing a nurse located in the small park area next to the ship.

Walk Around Balboa Park

Take a stroll around San Diego’s Balboa Park and admire its historic architecture and attractive landscaping. Visit one of the park’s 17 world-class museums, including the San Diego Natural History Museum, the San Diego Museum of Art, the San Diego Air and Space Museum, the San Diego Railroad Museum, and the San Diego Museum of Man.

Visit La Jolla Cove

If your ideal beach experience is less about sand and more about views, head to La Jolla Cove. This breathtaking coastline curves magnificently around the Pacific Ocean, and along with steep cliffs and rocky tide pools, you’ll see sea lions, seagulls, and other sea birds frolicking in the surf and on the rocks. The cove is next to La Jolla’s upscale shopping district, where you’ll find fine restaurants and designer boutiques. Adventure enthusiasts can go sea kayaking through the caves or snorkeling and scuba diving within the cove. 

What should I eat in San Diego?

During your cruise from San Diego, you can’t miss trying the authentic Mexican cuisine and fresh seafood you’ll find all over the city. San Diego is particularly known for its Baja fish tacos, which are made out of fish (often cod or mahi-mahi) fried in tasty batter, placed on a corn tortilla, then topped with a tangy white sauce and a heaping scoop of cabbage. 

Another iconic San Diego dish is the California burrito, which is stuffed with carne asada, french fries, guacamole, and cheese. The burger scene is also fantastic, and the battle for the best burger is usually between Hodad’s in Ocean Beach and Rocky’s in Pacific Beach. If you’re in the mood for seafood, try some fresh fish or locally caught spiny lobster (when it’s in season) at one of the many restaurants in Point Loma, the Gaslamp Quarter, or La Jolla.

What’s the history and culture of San Diego?

San Diego was discovered by Spanish explorer Juan Rodriguez Cabrillo in 1542, but before the Spanish settled there, the area was inhabited by Native Americans, specifically the Diegueño, Luiseño, Cahuilla, and Cupeño people. In 1769, the first mission was established. Control of the mission was taken over by Mexico in 1834, and it wasn’t until the United States incorporated California in 1846 that San Diego became a part of the country. 

Today, San Diego is known for its laid-back attitude, and its surf and beach culture are front and center when it comes to things to do. The city’s economy is mostly concentrated in the military and defense industries, as there are multiple naval bases in the area. Tourism also plays a major role in the city, as do biotech and telecommunication services.

Where can I go shopping in San Diego?

The mecca of all malls in the city is Fashion Valley, located in Mission Valley. Fashion Valley is home to several department stores, brand names, and luxury brands like Louis Vuitton, Burberry, and Balenciaga. Soak in some of the Southern California sunshine as you walk between stores at this open-air mall. 

For unique boutiques and eclectic shops, including San Diego’s most famous hat store, head to the uptown neighborhood of Hillcrest. The Gaslamp Quarter, which is located within walking distance from San Diego Harbor, is home to a number of popular shops and locally owned boutiques.

How can I get around San Diego?

The San Diego Trolley is a scenic way to travel around the city. It connects the Gaslamp Quarter with Old Town San Diego and some of the outer edges of the city limits. You’ll find many taxi ranks around downtown San Diego, popular beach areas, and the Port of San Diego. Take the Coaster to visit some of the coastal suburbs and their charming downtown areas. You can also use the Sprinter, a light rail line that connects the western coast with some of the more inland areas, such as San Marcos and Escondido. 

What are the currency and tipping customs?

San Diego uses the U.S. dollar, and credit cards are widely accepted. Before you get in a taxi, make sure it accepts credit cards, since some drivers only take cash. Some smaller food stands may only accept cash as well, so make sure you always have cash on hand. ATMs are located all over the city. Tipping in San Diego is similar to the rate the rest of the United States uses, at 15% to 20% of the total bill. 

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Panama Canal (Full Transit)

The Panama Canal is both an engineering masterpiece and a natural wonder. Connecting the Atlantic and Pacific oceans, the passageway crosses the huge, man-made Gatun Lake and the amazing Gaillard Cut, blasted out of solid mountainside. The great locks raise and lower your ship along a 50-mile waterway -- sometimes with just inches to spare on either side.

cruise panama canal from san diego

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  3. Panama Canal Cruises from San Diego, California 2024/2025

    Panama Canal Cruises Highlights. Colon, Panama: As the Caribbean entry point to the CanalCanal, Colon is a city of contrasts.Near the port, you'll find shopping centers for a quick retail therapy session. For the more adventurous, the ruins of Fort San Lorenzo, a UNESCO World Heritage Site, offer a glimpse into the region's colonial past.

  4. The Ultimate Guide to Panama Canal Cruises From San Diego & Los Angeles

    Cabo San Lucas, Mexico. Panama Canal cruises from San Diego or Los Angeles first stop in Mexico's Baja California Peninsula in Cabo San Lucas, where you can spend the day enjoying fish tacos and a margarita while soaking up the sun on a sandy beach.. If you're looking for a little more activity, take a catamaran, kayak, or jet ski out to Land's End, home to rock formations and some of ...

  5. Cruises from San Diego through the Panama Canal

    October 18, 2025: 14-night Panama Canal cruise on Norwegian Cruise Line. One-way from San Diego to Miami (Florida). Visit Cabo San Lucas (Mexico), Acapulco (Mexico), Puerto Quetzal (Guatemala), Panama City (Panama), Cartagena (Colombia) and Grand Cayman (Cayman Islands). November 1, 2025: 17-night Panama Canal cruise on Holland America Line.

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    The leader in the Panama Canal. From ships custom built to sail the massive locks to immersive onboard programs and onshore adventures that inspire, Princess is the number one way to explore this epic phenomenon. We've sailed the Panama Canal since 1967 and we have more itinerary choices and departures of any cruise line in the region.

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  9. Explore the Panama Canal on a Holland America Cruise

    Panama Canal Cruises. Experience one of the wonders of the modern world on Holland America Line's Panama Canal cruises. Our Panama cruise itineraries depart from both east and west coasts for loads of convenient options. A cruise to the Panama Canal is an incredible experience, worthy of any bucket list as you travel between oceans.

  10. 15-DAY PANAMA CANAL

    JAN 3 - JAN 18, 2025. DEPARTS : San Diego, California, US. ARRIVES : Fort Lauderdale, Florida, US. Pack in a lifetime of adventure on a cruise that sweeps to our exquisite private island paradise, Half Moon Cay, visits vibrant Cartagena and fully transits the Panama Canal. DATES.

  11. 16-Day Panama Canal from San Diego, California

    1.800.377.9383. QUICK. FREE. EASY. Personal Quote. Itinerary for Eurodam: 16-Day Panama Canal from San Diego, California to Panama Canal with Holland America Line. View deals, rates and port information.

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    from San Diego, California. Sailing. October, 2025. Journey through the world's best shortcut, the Panama Canal. Savor a wide range of delicious dining options on board. 8 Ports of Call. San Diego, California. Cabo San Lucas, Mexico. Acapulco, Mexico.

  13. Royal Caribbean Panama Canal Cruise, 16 Nights From San Diego, Radiance

    See low rates on this 16 Night Royal Caribbean Panama Canal departing San Diego 10/4/2025 on the Radiance of the Seas. Book online with iCruise.com or call 1-800-427-8473.

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  15. 15 Night Panama Canal Cruise from San Diego

    Day 16 - Saturday - Feb 3, 2024. See details and pricing for the Zaandam 15 Night Panama Canal Cruise sailing January 19, 2024 from San Diego. Book Holland America Line online or call 1-800-427-8473 - iCruise.com.

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    From 3,860. Save 29. Eastern Caribbean & Southern Seafarer Holiday. 17 Days Fort Lauderdale Fort Lauderdale. Operated By: Holland America. From 4,744. Save 35. Book online and enjoy exclusive savings on Holland America's 16 Day Panama Canal beginning your journey in San Diego and travelling through to Fort Lauderdale. 1000 season departures.

  17. Panama Canal Cruises

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  21. Holland America Panama Canal Cruise, 16 Nights From San Diego, Eurodam

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    See low rates on this 16 Night Holland America Panama Canal departing San Diego 10/4/2024 on the Nieuw Amsterdam. Book online with iCruise.com or call 1-800-427-8473. Save up to $100 on your next cruise. Sign In | Register ... 16 Night Panama Canal Cruise From San Diego, California, (United States) to Fort Lauderdale, Florida, (United States) ...